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We performed the transport of a breast cancer cell (MB231-TGFb) in a microvessel using high-resolution simulations. Using open-source imaging software Slicer3D and Meshmixer, the 3D surface mesh forming the cell membrane was reconstructed from confocal microscopic images. The Dissipative Particle Dynamics method is used to model the cell membrane. The extracellular fluid flow is modeled with the Immersed Boundary Method to solve the governing equations of the blood plasma. The unsteady flow is applied at the inlet of the microchannel with an oscillatory pattern. Our results showed that the extracellular flow patterns are highly dependent on the waveform profile. The oscillatory flow showed the creation of vortices that influence the cellular deformations in the microchannel. These results could have implications on the destination of the cancer cells during transport in physiological flows.

 

Image synthesis is a process of converting the input text, sketch, or other sources, i.e., another image or mask, into an image. It is an important problem in the computer vision field, where it has attracted the research community to attempt to solve this challenge at a high level to generate photorealistic images. Different techniques and strategies have been employed to achieve this purpose. Thus, the aim of this paper is to provide a comprehensive review of various image synthesis models covering several aspects. First, the image synthesis concept is introduced. We then review different image synthesis methods divided into three categories: image generation from text, sketch, and other inputs, respectively. Each sub-category is introduced under the proper category based upon the general framework to provide a broad vision of all existing image synthesis methods. Next, brief details of the benchmarked datasets used in image synthesis are discussed along with specifying the image synthesis models that leverage them. Regarding the evaluation, we summarize the metrics used to evaluate the image synthesis models. Moreover, a detailed analysis based on the evaluation metrics of the results of the introduced image synthesis is provided. Finally, we discuss some existing challenges and suggest possible future research directions. 

Abstract A plethora of approaches have been proposed for joint entity-relation (ER) extraction. Most of these methods largely depend on a large amount of manually annotated training data. However, manual data annotation is time-consuming, labor-intensive, and error-prone. Human beings learn using both data (through induction) and knowledge (through deduction). Answer Set Programming (ASP) has been a widely utilized approach for knowledge representation and reasoning that is elaboration tolerant and adept at reasoning with incomplete information. This paper proposes a new approach, ASP-enhanced Entity-Relation extraction (ASPER), to jointly recognize entities and relations by learning from both data and domain knowledge. In particular, ASPER takes advantage of the factual knowledge (represented as facts in ASP) and derived knowledge (represented as rules in ASP) in the learning process of neural network models. We have conducted experiments on two real datasets and compare our method with three baselines. The results show that our ASPER model consistently outperforms the baselines. 

Modeling corrosion growth for complex systems such as the oil refinery system is a major challenge since the corrosion process of oil and gas pipelines are inherently stochastic and depends on many factors including exposures to environmental conditions, operating conditions, and electrochemical reactions. Moreover, the number of sensors is usually limited, and sensor data are incomplete and scattering, which hinders the capability of capturing the corrosion growth behaviors. Therefore, this paper proposes Multi-sensor Corrosion Growth Model with Latent Variables to predict the corrosion growth process in oil refinery piping. The proposed model is a combination of the hierarchical clustering algorithm and the vector autoregression (VAR) model. The clustering algorithm aims to find the hidden (i.e., latent) data clusters of the measured time series data, from which the time series from the same cluster will be included in the VAR model to predict the corrosion depth from multiple sensors. The model can capture the relationship between sensor time series data and identify latent variables. A real case study of an oil refinery system, in which in-line inspection (ILI) data were collected, was utilized to validate model. Regarding corrosion growth prediction, the paper compared the prediction accuracy of VAR model with other three forms of power law model, which is widely accepted to expect the time-dependent depth of corrosion such as power function (PF), PF with initiation time of corrosion (PFIT), and PF with initiation time of corrosion and covariates (PFCOV). The results showed that VAR model has the lowest prediction error based on the mean absolute percentage error (MAPE) evaluation for test data. Finally, the proposed model is believed to be useful for dealing with a complex system that has a variety of corrosion growth behaviors, such as the oil refinery system, as well as it can be applied in other real-time applications. 

Public speaking is one of the most important ways to share ideas with many people in different domains such as education, training, marketing, or healthcare. Being able to master this skill allows the speaker to clearly advocate for their subject and greatly influence others. However, most of the population reported having public speaking anxiety or glossophobia, which prevents them from effectively conveying their messages to others. One of the best solutions is to have a safe and private space to practice speaking in front of others. As a result, this research work is proposed with the overarching goal of providing people with virtual environments to practice in front of simulated audiences. In addition, the proposed work will aim to have live audience feedback and speech analysis details which could be useful for the users. The experiments via a user study provide insights into the proposed public speaking simulator.